Kateřina Holubová gained her Master’s degree in Terrestrial Ecology at Charles University in Prague in 2015. Moreover, Mr Hošek has been serving as Vice President and Council member at the EUROPARC Federation since 2014, and as the Council member of International Union for Conservation of Nature since 2012. Later on, he worked at the Ministry of the Environment of the Czech Republic as Director General for Nature Conservation – Head of Directorate of Nature and Landscape Protection during 2013-2014. He was responsible for scientific and technical coordination of designation Natura 2000 network in the country, and international relationships including representation of the Czech Republic in the nature conservation at European level. longa.Michael Hošek is co-owner and managing partner of the INTEGRA Group ( ), mainly focused on projects related to biodiversity conservation and capacity development in the EU and its candidate and associated countries.īetween 2002 – 2013, Mr Hošek worked at the Nature Conservation Agency of the Czech Republic, where he was Deputy Director – Head of Division of Nature and the Landscape Documentation. longa for defense and environmental stress tolerance via production of secondary metabolites, which are associated with the wide range of medicinal properties in C. These mechanisms are crucial for perennial and rhizomatous plants such as C. longa revealed evolution in genes associated with secondary metabolism, plant phytohormones signaling, and various biotic and abiotic stress tolerance responses. Using 5,388 orthogroups, the comparative evolutionary analysis performed across 17 species including C. longa was resolved through a comprehensive genome-wide analysis including 16 other plant species. The draft genome assembly had a size of 1.02"‰Gbp with ~70% repetitive sequences, and contained 50,401 coding gene sequences. For comprehensive gene set prediction and for insights into its gene expression, transcriptome sequencing of leaf tissue was also performed. longa, belonging to Zingiberaceae plant family, constructed using 10x Genomics linked reads and Oxford Nanopore long reads. In this study, we present the draft genome sequence of C. However, the absence of a reference genome sequence is a limiting factor in understanding the genomic basis of the origin of its medicinal properties. Our study provides a global view on RNA"“chromatin interactions in Arabidopsis and a rich resource for future investigations of regulatory roles of RNAs in gene expression and genome organization.Ĭurcuma longa, or turmeric, is traditionally known for its immense medicinal properties and has diverse therapeutic applications.
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We further show that some RNA"“chromatin interactions undergo alterations in response to biotic and abiotic stresses and that altered RNA"“chromatin interactions form co-regulatory networks. Many RNA"“chromatin interactions tend to positively correlate with DNA"“DNA interactions, suggesting their mutual influence and reinforcement. Cis and intra-chromosomal interactions are mainly mediated by protein-coding RNAs, whereas inter-chromosomal interactions are primarily mediated by non-coding RNAs. We identified more than 10,000 RNA"“chromatin interactions mediated by protein-coding RNAs and non-coding RNAs. Here we adapted a sequencing-based technique to profile RNA"“chromatin interactions at a genome-wide scale in Arabidopsis seedlings. It is increasingly evident that various RNAs can bind chromatin to regulate gene expression and genome organization.